Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003231 | 0.61 | POLB (0.30) | — | |
| SCHEMBL27604301 | 0.60 | KDM4E (0.44) | KDM4E | |
| SCHEMBL28318621 | 0.60 | KDM4E (0.41) | KDM4E | |
| SCHEMBL29379160 | 0.58 | — | — | |
| SCHEMBL22068855 | 0.55 | POLB (0.39) | GPR35KDM4EPKM | |
| SCHEMBL9408075 | 0.54 | TSHR (0.33) | GPR35 | |
| SCHEMBL2428098 | 0.53 | — | — | |
| SCHEMBL4584130 | 0.53 | GSK3B (0.59) | GPR35 | |
| SCHEMBL3705659 | 0.53 | GPR35 (0.39) | GPR35KDM4EPKM | |
| Bromide SCHEMBL9185506 | 0.53 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |