Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 13/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041123 | 0.81 | GSK3B (0.55) | GSK3BGPR35TSHRDAO | |
| SCHEMBL2690137 | 0.79 | POLB (0.52) | GSK3BGPR35TSHRPOLBTDP1 | |
| SCHEMBL2982713 | 0.78 | GSK3B (0.57) | GSK3BGPR35TSHRPOLB | |
| SCHEMBL3281960 | 0.78 | GPR35 (0.47) | GSK3BGPR35TSHRPOLBTDP1 | |
| SCHEMBL1973884 | 0.78 | GPR35 (0.47) | GSK3BGPR35TSHRPOLBTDP1 | |
| SCHEMBL321098 | 0.76 | GPR35 (0.60) | GSK3BGPR35POLBTDP1L3MBTL1 | |
| SCHEMBL8135224 | 0.76 | ALDH1A1 (0.47) | GSK3BGPR35TSHRPOLBTDP1 | |
| SCHEMBL18152986 | 0.76 | GPR35 (0.46) | GSK3BGPR35TSHRPOLBTDP1 | |
| SCHEMBL6784082 | 0.75 | GSK3B (1.00) | GSK3BGPR35TSHRPTPN1 | |
| SCHEMBL16415737 | 0.74 | GSK3B (0.48) | GSK3BTSHRPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118594613-A | Hybrid aerogel-loaded polymer photocatalytic antibacterial agent and preparation method thereof | 吉林师范大学 | 2024-09-06 | — | — | CN | claimed |
| CN-1069164-C | Microbicidal compositions of dibromo-thiophene-carboxylic acid derivatives | BAYER AG (DE) | 2001-08-08 | — | — | CN | claimed |
| CN-1305708-A | Microbicidal compositions of dibromo-thiophene-carboxylic acid derivatives | BAYER AG (DE) | 2001-08-01 | — | — | CN | claimed |
| EP-0755185-B1 | Use of Dibromo-thiophen-carboxylic acid derivatives as microbicides | BAYER AG (DE) | 2000-12-13 | — | — | EP | claimed |
| US-5789437-A | Microbicidal compositions based on dibromo-thiophene-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | claimed |
| CN-1150378-A | Microbicidal compositions of dibromo-thiophene-carboxylic acid derivatives | BAYER AG (DE) | 1997-05-21 | — | — | CN | claimed |
| US-12133841-B2 | Heterocyclic compounds as kinase inhibitors, compositions comprising the heterocyclic compound, and methods of use thereof | JS INNOMED HOLDINGS LTD. (KY) | 2024-11-05 | — | — | US | disclosed |
| CN-118594613-A | Hybrid aerogel-loaded polymer photocatalytic antibacterial agent and preparation method thereof | 吉林师范大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-112638917-B | Heterocyclic compounds as kinase inhibitors, compositions comprising the same, and methods of use thereof | 捷思英达控股有限公司 | 2023-09-08 | — | — | CN | disclosed |
| US-20210188868-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS COMPRISING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF | JS INNOMED HOLDINGS LTD. (KY) | 2021-06-24 | — | — | US | disclosed |
| CN-112638917-A | Heterocyclic compounds as kinase inhibitors, compositions comprising the heterocyclic compounds, and methods of use thereof | 捷思英达控股有限公司 | 2021-04-09 | — | — | CN | disclosed |
| EP-3797109-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS COMPRISING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF | JS Innomed Holdings Ltd. (KY) | 2021-03-31 | — | — | EP | disclosed |
| EP-1968568-A2 | INHIBITORS OF Akt ACTIVITY | SmithKline Beecham Corporation (US) | 2008-09-17 | — | — | EP | disclosed |
| US-5789437-A | Microbicidal compositions based on dibromo-thiophene-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| US-5789437-A | Microbicidal compositions based on dibromo-thiophene-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| CN-1150378-A | Microbicidal compositions of dibromo-thiophene-carboxylic acid derivatives | BAYER AG (DE) | 1997-05-21 | — | — | CN | disclosed |
| CN-1150378-A | Microbicidal compositions of dibromo-thiophene-carboxylic acid derivatives | BAYER AG (DE) | 1997-05-21 | — | — | CN | disclosed |
| CN-1150378-A | Microbicidal compositions of dibromo-thiophene-carboxylic acid derivatives | BAYER AG (DE) | 1997-05-21 | — | — | CN | disclosed |
| EP-0755185-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995027397-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188868-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS COMPRISING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF | MAP3K11, MAP3K13, MAP3K1 | GSK3B 110/4885GPR35 2269/4885TSHR 3177/4885 |
| US-12133841-B2 | Heterocyclic compounds as kinase inhibitors, compositions comprising the heterocyclic compound, and methods of use thereof | MAP3K11, MAP3K13, MAP3K1 | GSK3B 110/4885GPR35 2269/4885TSHR 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.