Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.37 |
| ▸ | FLT1 | P17948 | 4/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577269 | 0.96 | FLT1 (0.39) | GNRHRKDRFLT1FGFR1EGFR | |
| SCHEMBL4301135 | 0.91 | GNRHR (0.43) | GNRHRCACNA1CPDE4DHTR2AHTR2C | |
| SCHEMBL30002533 | 0.91 | GNRHR (0.43) | GNRHRCACNA1CPDE4DHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL30425693 | 0.90 | GNRHR (0.43) | GNRHRCACNA1CPDE4DHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL3100373 | 0.90 | GNRHR (0.43) | GNRHRCACNA1CPDE4DHTR2AHTR2C | |
| SCHEMBL10300231 | 0.89 | FLT1 (0.39) | GNRHRKDRFLT1FGFR1EGFR | |
| SCHEMBL28892183 | 0.89 | CACNA1C (0.39) | GNRHREGFRCACNA1CPDE4DPDE4A | |
| SCHEMBL13577276 | 0.89 | GNRHR (0.39) | GNRHRKDRFLT1FGFR1EGFR | |
| SCHEMBL13577264 | 0.88 | MAPT (0.43) | GNRHRCACNA1CPDE4DPDE4APDE4B | |
| SCHEMBL13577279 | 0.86 | MAPT (0.37) | GNRHRCACNA1CPDE4DHTR2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |