Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301135 | 1.00 | GNRHR (0.43) | GNRHRGAAKDM4EMAPTCACNA1C | |
| Hydrochloric Acid SCHEMBL30425693 | 0.99 | GNRHR (0.43) | GNRHRGAAKDM4EMAPTCACNA1C | |
| Hydrochloric Acid SCHEMBL3100373 | 0.99 | GNRHR (0.43) | GNRHRGAAKDM4EMAPTCACNA1C | |
| SCHEMBL13577264 | 0.94 | MAPT (0.43) | GNRHRGAAKDM4EMAPTCACNA1C | |
| SCHEMBL13577265 | 0.91 | CACNA1C (0.38) | GNRHRGAAKDM4EMAPTCACNA1C | |
| SCHEMBL30002430 | 0.91 | GNRHR (0.38) | GNRHRCACNA1CKITHTR2AHTR2C | |
| SCHEMBL28892183 | 0.90 | CACNA1C (0.39) | GNRHRGAAKDM4EMAPTCACNA1C | |
| SCHEMBL13577269 | 0.90 | FLT1 (0.39) | GNRHRGAAKDM4EMAPTCACNA1C | |
| SCHEMBL13577210 | 0.89 | PTGS2 (0.37) | GNRHRGAAKDM4EMAPTCACNA1C | |
| SCHEMBL3100037 | 0.88 | NPC1 (0.44) | GNRHRGAAKDM4EMAPTCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440095-A | Preparation method of GnRH receptor antagonist Linzagolix | 中国药科大学 | 2024-08-06 | — | — | CN | claimed |
| CN-116178389-A | Preparation method of linagoli | 浙江科聚生物医药有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-121159412-A | Synthesis method of 5- (2, 3-difluoro-6-methoxybenzyloxy) -2-fluoro-4-methoxyaniline | 江西凯信生物医药有限公司 | 2025-12-19 | — | — | CN | disclosed |
| CN-121159412-A | Synthesis method of 5- (2, 3-difluoro-6-methoxybenzyloxy) -2-fluoro-4-methoxyaniline | 江西凯信生物医药有限公司 | 2025-12-19 | — | — | CN | disclosed |
| CN-118440095-A | Preparation method of GnRH receptor antagonist Linzagolix | 中国药科大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-118440095-A | Preparation method of GnRH receptor antagonist Linzagolix | 中国药科大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116178389-A | Preparation method of linagoli | 浙江科聚生物医药有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |