Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | PPARD | Q03181 | 8/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | CPT1A | P50416 | 4/20 | 0.49 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.49 |
| ▸ | CPT2 | P23786 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892197 | 1.00 | PPARG (0.51) | PPARGPPARDPPARAFABP4CPT1A | |
| SCHEMBL28892694 | 0.91 | FABP4 (0.52) | PPARGPPARDPPARAFABP4CPT1A | |
| SCHEMBL28892270 | 0.90 | FABP4 (0.50) | PPARGPPARDPPARAFABP4CPT1A | |
| SCHEMBL28892358 | 0.83 | FABP4 (0.59) | PPARGPPARDPPARAFABP4KMT2A | |
| SCHEMBL30002423 | 0.83 | FABP4 (0.59) | PPARGPPARDPPARAFABP4KMT2A | |
| SCHEMBL28892372 | 0.83 | PPARG (0.49) | PPARGPPARDPPARAFABP4KMT2A | |
| SCHEMBL28892466 | 0.80 | CPT1A (0.45) | PPARGPPARDPPARAFABP4CPT1A | |
| SCHEMBL28892561 | 0.79 | CPT1A (0.44) | PPARGPPARDPPARAFABP4CPT1A | |
| SCHEMBL28892559 | 0.77 | CPT1A (0.43) | PPARGPPARDPPARAFABP4CPT1A | |
| SCHEMBL30002912 | 0.76 | HTR6 (0.49) | FABP4CPT1ACPT1BCPT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |