Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30002552

CC(C)C[C@H](N)C(=O)N[C@@H](CC1CCNC1=O)C(N)=O.O=C(O)C(F)(F)F

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 4/20 0.43
▸ CTSB P07858 3/20 0.43
▸ CAPN1 P07384 1/20 0.41
▸ CTSV O60911 1/20 0.41
▸ CTSS P25774 1/20 0.41
▸ CTSK P43235 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24109107 0.93 CTSL (0.42) CTSLCTSBCAPN1
SCHEMBL30001755 0.93 CTSL (0.42) CTSLCTSBCAPN1
SCHEMBL24486589 0.93 CTSL (0.42) CTSLCTSBCAPN1
Hydrochloric Acid SCHEMBL30001949 0.92 CTSL (0.42) CTSLCTSBCAPN1
SCHEMBL29610180 0.89 CTSL (0.45) CTSLCTSBCAPN1CTSSCTSK
SCHEMBL23824251 0.86 CTSL (0.43) CTSLCTSBCAPN1CTSSCTSK
SCHEMBL23824248 0.86 CTSL (0.43) CTSLCTSBCAPN1CTSSCTSK
SCHEMBL25761960 0.82 CTSL (0.43) CTSLCTSBCAPN1
SCHEMBL15985646 0.82 CTSL (0.45) CTSLCTSBCAPN1
SCHEMBL24690763 0.82 CTSL (0.45) CTSLCTSBCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122153-A1 Protease Inhibitors as Antivirals ACEA Therapeutics, Inc. (US) 2025-04-17 — — US disclosed
US-11987554-B2 Protease inhibitors as antivirals VIVASOR, INC. (US) 2024-05-21 — — US disclosed
EP-4347034-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2024-04-10 — — EP disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 — — US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 — — US disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 — — US disclosed
WO-2022256434-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2022-12-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122153-A1 Protease Inhibitors as Antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CAPN1 158/4885
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CAPN1 158/4885
US-11753373-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CAPN1 158/4885
US-11987554-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CAPN1 158/4885
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885CAPN1 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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