Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002627 | 0.93 | HTR6 (0.46) | HTR6ALDH1A1POLBTP53SMN1; SMN2 | |
| SCHEMBL28892335 | 0.93 | HTR6 (0.46) | HTR6ALDH1A1POLBTP53SMN1; SMN2 | |
| SCHEMBL30002599 | 0.90 | HTR6 (0.47) | HTR6POLBL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL28892345 | 0.89 | MEN1 (0.40) | HTR6ALDH1A1POLBTP53L3MBTL1 | |
| SCHEMBL30002550 | 0.83 | HTR6 (0.43) | HTR6ALDH1A1POLBTP53L3MBTL1 | |
| SCHEMBL28892365 | 0.82 | HTR6 (0.48) | HTR6ALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL28959478 | 0.82 | HTR6 (0.49) | HTR6ALDH1A1POLBTP53SMN1; SMN2 | |
| SCHEMBL30002434 | 0.82 | HTR6 (0.49) | HTR6ALDH1A1POLBTP53SMN1; SMN2 | |
| SCHEMBL30002820 | 0.80 | HTR6 (0.49) | HTR6ALDH1A1POLBTP53L3MBTL1 | |
| SCHEMBL3116334 | 0.77 | NR1H3 (0.44) | ALDH1A1TP53SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |