Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.43 |
| ▸ | FABP4 | P15090 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | BRD1 | O95696 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28959478 | 0.91 | HTR6 (0.49) | HTR6FABP4KMT2AALDH1A1TP53 | |
| SCHEMBL30002434 | 0.91 | HTR6 (0.49) | HTR6FABP4KMT2AALDH1A1TP53 | |
| SCHEMBL28892345 | 0.85 | MEN1 (0.40) | HTR6FABP4KMT2AALDH1A1TP53 | |
| SCHEMBL28892335 | 0.83 | HTR6 (0.46) | HTR6FABP4KMT2AALDH1A1TP53 | |
| SCHEMBL30002627 | 0.83 | HTR6 (0.46) | HTR6FABP4KMT2AALDH1A1TP53 | |
| SCHEMBL30002738 | 0.83 | HTR6 (0.46) | HTR6FABP4ALDH1A1TP53TSHR | |
| SCHEMBL28892442 | 0.82 | FABP4 (0.43) | HTR6FABP4KMT2AALDH1A1TP53 | |
| SCHEMBL30002530 | 0.81 | HTR6 (0.48) | HTR6FABP4ALDH1A1TP53TSHR | |
| SCHEMBL30002599 | 0.81 | HTR6 (0.47) | HTR6FABP4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28892365 | 0.80 | HTR6 (0.48) | HTR6FABP4KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |