Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 15/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 13/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894262 | 1.00 | MKNK1 (0.38) | MKNK1MKNK2MAPK1LMNASMN1; SMN2 | |
| SCHEMBL30002021 | 0.85 | HRH3 (0.35) | HRH3NPC1 | |
| SCHEMBL30001992 | 0.78 | TTK (0.60) | MKNK1 | |
| SCHEMBL1291499 | 0.77 | HDAC1 (0.38) | HRH3NPC1 | |
| SCHEMBL17467249 | 0.76 | KDM4E (0.39) | LMNASMN1; SMN2HRH3NPC1 | |
| SCHEMBL31497497 | 0.75 | DGAT1 (0.37) | HRH3NPC1 | |
| SCHEMBL17466924 | 0.74 | HRH3 (0.53) | SMN1; SMN2HRH3 | |
| SCHEMBL13737735 | 0.74 | DGAT1 (0.34) | HRH3NPC1 | |
| SCHEMBL17466967 | 0.73 | EGFR (0.37) | MAPK1LMNANPC1 | |
| SCHEMBL2357255 | 0.73 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368364-B | 7H-pyrrolo [2,3-d ] pyrimidine derivatives, preparation method and application thereof | 四川大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-115368364-A | 7H-pyrrolo [2,3-d ] pyrimidine derivative and preparation method and application thereof | 四川大学 | 2022-11-22 | — | — | CN | disclosed |