Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL748900 | 0.88 | SHBG (0.48) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL3003262 | 0.78 | SHBG (0.41) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL7973965 | 0.78 | EPHX1 (0.40) | SHBGEPHX1ACHETP53 | |
| SCHEMBL8076025 | 0.78 | SHBG (0.44) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL2419110 | 0.78 | SHBG (0.44) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL4653053 | 0.75 | SHBG (0.40) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL22984956 | 0.75 | SHBG (0.36) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL6014415 | 0.74 | EPHX1 (0.41) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL20600325 | 0.74 | SHBG (0.41) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL20049927 | 0.74 | SHBG (0.41) | SHBGEPHX1TP53IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |