Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL748900 | 0.84 | SHBG (0.48) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL11694887 | 0.83 | SHBG (0.44) | SHBGHTTEPHX1CYP1A2EPHX2 | |
| SCHEMBL3000356 | 0.82 | SHBG (0.38) | SHBGCYP1A2IDO1TDO2 | |
| SCHEMBL19200234 | 0.78 | SHBG (0.39) | SHBGHTTEPHX1CYP1A2EPHX2 | |
| SCHEMBL3000277 | 0.78 | SHBG (0.39) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL18538980 | 0.75 | SHBG (0.37) | SHBGHTTCYP1A2EPHX2 | |
| SCHEMBL8076025 | 0.75 | SHBG (0.44) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL2419110 | 0.75 | SHBG (0.44) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL2999486 | 0.72 | SHBG (0.48) | SHBGEPHX1TP53IDO1TDO2 | |
| SCHEMBL25086835 | 0.72 | SHBG (0.32) | SHBGEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |