SCHEMBL30002772

SCHEMBL30002772

O=C1C=C(Cl)C(=O)c2ccc(O)cc21

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.57
ESR1 P03372 8/20 0.57
MAOA P21397 2/20 0.57
MAOB P27338 2/20 0.57
UGT1A1 P22309 1/20 0.57
AURKA O14965 2/20 0.47
AURKB Q96GD4 1/20 0.47
TTR P02766 1/20 0.43
PTPRC P08575 1/20 0.43
P4HB P07237 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
BACE1 P56817 1/20 0.40
DYRK1A Q13627 1/20 0.38
PRKCI P41743 1/20 0.38
BCL2 P10415 1/20 0.38
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23271753 1.00 ESR2 (0.57) ESR2ESR1MAOAMAOBUGT1A1
SCHEMBL28453465 0.92 ESR2 (0.57) ESR2ESR1MAOAMAOBUGT1A1
SCHEMBL9628309 0.81 S100A4 (0.52) ESR2ESR1AURKAAURKBPTPRC
SCHEMBL5811756 0.80 ESR2 (0.61) ESR2ESR1MAOAMAOBUGT1A1
SCHEMBL30004162 0.80 ESR2 (0.61) ESR2ESR1MAOAMAOBUGT1A1
SCHEMBL8773066 0.80 S100A4 (0.56) AURKAAURKBPTPRCDYRK1A
SCHEMBL11013388 0.77 ESR1 (0.57) ESR2ESR1MAOAMAOBUGT1A1
SCHEMBL9628267 0.77 PTPN1 (0.44) AURKAAURKBCA1CA2CA7
SCHEMBL23271815 0.77 ESR2 (0.57) ESR2ESR1MAOAMAOBUGT1A1
SCHEMBL7815913 0.77 MAOA (0.53) MAOAMAOBAURKAAURKBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed