Sugi Predict

Sugi Predict / Compounds / SCHEMBL30002850

SCHEMBL30002850

SCHEMBL30002850

C[Si](O[Si](c1ccccc1)(c1ccccc1)c1ccccc1)(O[Si](c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.38
▸ ESR2 Q92731 1/20 0.38
▸ NR1H2 P55055 2/20 0.31
▸ NR1H3 Q13133 2/20 0.31
▸ DUT P33316 1/20 0.31
▸ CA4 P22748 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94183 0.93 ESR1 (0.34) ESR1ESR2DUT
SCHEMBL10626857 0.89 ESR1 (0.36) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL28705381 0.87 ESR1 (0.33) ESR1ESR2
SCHEMBL13621322 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL19741576 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL2394267 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL2048191 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3DUT
SCHEMBL4609458 0.82 ESR1 (0.31) ESR1ESR2
SCHEMBL335769 0.81 TSHR (0.35) ESR1ESR2DUTCA4MAPT
SCHEMBL419488 0.80 ESR1 (0.38) ESR1ESR2NR1H2NR1H3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347702-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2024-04-10 — — EP disclosed
WO-2022253413-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2022-12-08 — — WO disclosed