SCHEMBL30002901

SCHEMBL30002901

CCCCc1ccc(-c2nc(C(C)C)c(CCC(O)c3ccc(OCCO)c(C)c3)s2)cc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DCK P27707 6/20 0.37
PPARD Q03181 7/20 0.36
PPARA Q07869 3/20 0.36
PPARG P37231 2/20 0.36
PTPN1 P18031 1/20 0.34
UCHL3 P15374 2/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
GCGR P47871 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658340 1.00 DCK (0.37) DCKPPARDPPARAPPARGPTPN1
SCHEMBL24658310 0.90 PPARD (0.38) DCKPPARDPPARAPPARGMAPT
SCHEMBL30003418 0.90 PPARD (0.38) DCKPPARDPPARAPPARGMAPT
SCHEMBL30003479 0.87 PPARD (0.39) PPARDPPARAPPARGUCHL3GCGR
SCHEMBL24658342 0.87 PPARD (0.39) PPARDPPARAPPARGUCHL3GCGR
SCHEMBL23870963 0.86 PPARD (0.49) PPARDPPARAPPARG
SCHEMBL23870961 0.86 PPARD (0.49) PPARDPPARAPPARG
SCHEMBL24658343 0.86 TLR8 (0.39) DCKPPARDPPARAPPARGPTPN1
SCHEMBL23870983 0.86 PPARD (0.49) PPARDPPARAPPARG
SCHEMBL30003630 0.86 TLR8 (0.39) DCKPPARDPPARAPPARGPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333379-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2025-10-30 US disclosed
US-12297168-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2025-05-13 US disclosed
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2024-06-20 US disclosed
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-11634387-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2023-04-25 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A DCK 1948/4885PPARD 332/4885PPARA 94/4885
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, FABP1, CPT1A DCK 1948/4885PPARD 332/4885PPARA 94/4885
US-11634387-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A DCK 1948/4885PPARD 332/4885PPARA 94/4885
US-20250333379-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A DCK 1948/4885PPARD 332/4885PPARA 94/4885
US-12297168-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A DCK 1948/4885PPARD 332/4885PPARA 94/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A DCK 1948/4885PPARD 332/4885PPARA 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.