SCHEMBL30003630

SCHEMBL30003630

COc1ccc(-c2nc(C(C)C)c(CCC(O)c3ccc(OCCCO)c(C)c3)s2)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.39
DCK P27707 2/20 0.37
ALOX5 P09917 2/20 0.36
PPARD Q03181 6/20 0.36
PPARG P37231 4/20 0.36
PPARA Q07869 4/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35
PTPN1 P18031 1/20 0.35
TP53 P04637 3/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658343 1.00 TLR8 (0.39) TLR8DCKALOX5PPARDPPARG
SCHEMBL24658310 0.88 PPARD (0.38) DCKALOX5PPARDPPARGPPARA
SCHEMBL30003418 0.88 PPARD (0.38) DCKALOX5PPARDPPARGPPARA
SCHEMBL30002901 0.86 DCK (0.37) DCKPPARDPPARGPPARAPTPN1
SCHEMBL24658340 0.86 DCK (0.37) DCKPPARDPPARGPPARAPTPN1
SCHEMBL24658344 0.86 DCK (0.36) DCKPPARDPPARGPPARAMAPT
SCHEMBL30004364 0.86 DCK (0.36) DCKPPARDPPARGPPARAMAPT
SCHEMBL23870983 0.84 PPARD (0.49) PPARDPPARGPPARA
SCHEMBL23870961 0.84 PPARD (0.49) PPARDPPARGPPARA
SCHEMBL23870963 0.84 PPARD (0.49) PPARDPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333379-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2025-10-30 US disclosed
US-12297168-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2025-05-13 US disclosed
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2024-06-20 US disclosed
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-11634387-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2023-04-25 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A TLR8 723/4885DCK 1948/4885ALOX5 383/4885
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, FABP1, CPT1A TLR8 723/4885DCK 1948/4885ALOX5 383/4885
US-11634387-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A TLR8 723/4885DCK 1948/4885ALOX5 383/4885
US-20250333379-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A TLR8 723/4885DCK 1948/4885ALOX5 383/4885
US-12297168-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A TLR8 723/4885DCK 1948/4885ALOX5 383/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A TLR8 723/4885DCK 1948/4885ALOX5 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.