Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973341 | 0.85 | CYP1A2 (0.33) | CYP1A2SHBGMEN1ALDH1A1LMNA | |
| SCHEMBL2991590 | 0.79 | CYP1A2 (0.41) | CYP1A2SHBGMEN1ALDH1A1LMNA | |
| SCHEMBL10876431 | 0.79 | CYP1A2 (0.36) | CYP1A2SHBGMEN1ALDH1A1LMNA | |
| SCHEMBL10876420 | 0.79 | CYP1A2 (0.36) | CYP1A2SHBGMEN1ALDH1A1LMNA | |
| SCHEMBL1396813 | 0.78 | ALDH1A1 (0.39) | CYP1A2SHBGMEN1ALDH1A1LMNA | |
| SCHEMBL8498087 | 0.78 | CYP1A2 (0.44) | CYP1A2SHBGMEN1ALDH1A1LMNA | |
| SCHEMBL28157000 | 0.78 | CYP1A2 (0.39) | CYP1A2SHBGMEN1ALDH1A1LMNA | |
| SCHEMBL14048439 | 0.76 | CYP1A2 (0.32) | CYP1A2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL10779865 | 0.74 | CYP1A2 (0.40) | CYP1A2SHBG | |
| SCHEMBL8759751 | 0.74 | KDM4E (0.38) | CYP1A2SHBGMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |