SCHEMBL30003055

SCHEMBL30003055

CCCCCc1cccc2c1C(=O)C=CC2=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.51
POLK Q9UBT6 2/20 0.51
POLL Q9UGP5 2/20 0.51
POLH Q9Y253 2/20 0.51
NR1H2 P55055 1/20 0.48
NR1H3 Q13133 1/20 0.48
ELANE P08246 5/20 0.46
CTSG P08311 3/20 0.46
TOP1 P11387 2/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
AURKA O14965 1/20 0.44
USP2 O75604 1/20 0.44
TRPA1 O75762 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
P4HB P07237 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23271654 1.00 POLM (0.51) POLMPOLKPOLLPOLHNR1H2
SCHEMBL23271864 0.95 POLM (0.49) POLMPOLKPOLLPOLHNR1H2
SCHEMBL30004164 0.95 POLM (0.49) POLMPOLKPOLLPOLHNR1H2
SCHEMBL16284304 0.88 TOP1 (0.49) POLMPOLKPOLLPOLHNR1H2
SCHEMBL19646698 0.82 IDO1 (0.53) POLMPOLKPOLLPOLHTOP1
SCHEMBL12096345 0.79 ELANE (0.62) NR1H2NR1H3ELANECTSGPTPN1
SCHEMBL30003946 0.78 ALDH1A1 (0.53) NR1H2NR1H3ELANECTSGKDM4E
SCHEMBL23271901 0.78 ALDH1A1 (0.53) NR1H2NR1H3ELANECTSGKDM4E
SCHEMBL28357045 0.78 ELANE (0.43) POLMPOLKPOLLPOLHNR1H2
SCHEMBL28345511 0.78 ELANE (0.43) POLMPOLKPOLLPOLHNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed