SCHEMBL28345511

SCHEMBL28345511

CCCCCCc1ccc2c(c1CCCCCC)C(=O)C=CC2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.43
CTSG P08311 3/20 0.43
POLM Q9NP87 2/20 0.43
POLK Q9UBT6 2/20 0.43
POLL Q9UGP5 2/20 0.43
POLH Q9Y253 2/20 0.43
ACHE P22303 1/20 0.42
BACE1 P56817 1/20 0.42
TYR P14679 2/20 0.41
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28357045 1.00 ELANE (0.43) ELANECTSGPOLMPOLKPOLL
SCHEMBL23271654 0.78 POLM (0.51) ELANECTSGPOLMPOLKPOLL
SCHEMBL30003055 0.78 POLM (0.51) ELANECTSGPOLMPOLKPOLL
SCHEMBL1864583 0.77 ELANE (0.42) ELANECTSGTYRNR1H2NR1H3
SCHEMBL11708641 0.77 ELANE (0.45) ELANECTSGTYRNR1H2NR1H3
SCHEMBL11328017 0.75 TYR (0.57) ACHETYRMEN1TP53CYP3A4
SCHEMBL11331495 0.75 TYR (0.57) ACHETYRMEN1TP53CYP3A4
SCHEMBL11337178 0.75 TYR (0.57) ACHETYRMEN1TP53CYP3A4
SCHEMBL30876168 0.75 TYR (0.57) ACHETYRMEN1TP53CYP3A4
SCHEMBL7571565 0.75 TYR (0.57) ACHETYRMEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642695-A N-type star polycyclic conjugated aromatic hydrocarbon and synthetic method thereof 重庆工商大学 2020-01-03 CN disclosed