SCHEMBL30003082

SCHEMBL30003082

COc1ccc2c(c1)C(=O)C(O)=C(C)C2=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 3/20 0.51
PRKACA P17612 1/20 0.50
PRKACG P22612 1/20 0.50
PRKACB P22694 1/20 0.50
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA4 P22748 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
IDO1 P14902 2/20 0.47
USP8 P40818 2/20 0.47
PTPN1 P18031 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
ALDH1A1 P00352 2/20 0.44
NQO1 P15559 2/20 0.43
POR P16435 2/20 0.43
ME2 P23368 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23271650 1.00 LCK (0.51) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL5810326 0.89 LCK (0.56) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL30003654 0.87 MAOA (0.57) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL23271658 0.87 MAOA (0.57) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL5811522 0.82 CDC25A (0.66) LCKPRKACAPRKACGPRKACBCA1
SCHEMBL9177813 0.81 ESR1 (0.51) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL7451901 0.81 CA1 (0.57) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL2252533 0.81 CA1 (0.57) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL30583631 0.79 PPARG (0.49) LCKPRKACAPRKACGPRKACBESR1
SCHEMBL29173163 0.79 ESR1 (0.67) LCKPRKACAPRKACGPRKACBESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed