SCHEMBL30003265

SCHEMBL30003265

Cc1ccc2cc3ccccc3c(OCCOc3ccccc3)c2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP2A6 P11509 1/20 0.42
DRD2 P14416 6/20 0.41
DRD4 P21917 6/20 0.41
DRD3 P35462 5/20 0.41
CXCR2 P25025 1/20 0.41
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
ADRB2 P07550 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRB1 P08588 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
CHRM3 P20309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23271737 1.00 KCNA3 (0.42) KCNA3TDP1CYP2A6DRD2DRD4
SCHEMBL23271651 0.87 KCNA3 (0.51) KCNA3TDP1DRD2DRD4DRD3
SCHEMBL30003180 0.87 KCNA3 (0.51) KCNA3TDP1DRD2DRD4DRD3
SCHEMBL30003120 0.87 CYP2A6 (0.39) TDP1CYP2A6KDM4EMAPTLMNA
SCHEMBL23271740 0.87 CYP2A6 (0.39) TDP1CYP2A6KDM4EMAPTLMNA
SCHEMBL23089920 0.85 CYP2A6 (0.40) TDP1CYP2A6KDM4EMAPTALDH1A1
SCHEMBL29368618 0.85 CYP2A6 (0.40) TDP1CYP2A6KDM4EMAPTALDH1A1
SCHEMBL23271868 0.84 DRD2 (0.45) KCNA3DRD2DRD4DRD3GRIN2D
SCHEMBL30003363 0.84 DRD2 (0.45) KCNA3DRD2DRD4DRD3GRIN2D
SCHEMBL23271672 0.84 ACHE (0.38) TDP1CYP2A6HTR1AHTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed