SCHEMBL30003578

SCHEMBL30003578

NC1=C(Cl)C(=O)c2cc(O)ccc2C1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 10/20 0.61
ESR1 P03372 9/20 0.61
MAOA P21397 1/20 0.61
UGT1A1 P22309 1/20 0.61
MAOB P27338 1/20 0.61
TDP2 O95551 1/20 0.60
NSD2 O96028 1/20 0.60
HK1 P19367 1/20 0.60
PAX8 Q06710 1/20 0.60
TTR P02766 1/20 0.46
S100A4 P26447 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23271822 1.00 ESR2 (0.61) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL23271760 0.86 ESR2 (0.74) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL30003606 0.86 ESR2 (0.74) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL30003548 0.81 TDP2 (0.64) TDP2NSD2HK1PAX8S100A4
SCHEMBL7818893 0.81 TDP2 (0.64) TDP2NSD2HK1PAX8S100A4
SCHEMBL7819127 0.81 TDP2 (0.64) TDP2NSD2HK1PAX8S100A4
SCHEMBL7812020 0.78 TDP2 (0.60) MAOAMAOBTDP2NSD2HK1
SCHEMBL7812173 0.78 TDP2 (0.60) MAOAMAOBTDP2NSD2HK1
SCHEMBL30003080 0.78 TDP2 (0.60) MAOAMAOBTDP2NSD2HK1
Anthraflavicacid SCHEMBL124974 0.77 ESR2 (1.00) ESR2ESR1MAOAUGT1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed