SCHEMBL30003548

SCHEMBL30003548

NC1=C(Cl)C(=O)c2cc(Cl)ccc2C1=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.64
NSD2 O96028 2/20 0.64
HK1 P19367 1/20 0.64
PAX8 Q06710 1/20 0.64
S100A4 P26447 4/20 0.59
HSP90AA1 P07900 1/20 0.46
PPOX P50336 1/20 0.44
IDO1 P14902 1/20 0.41
DNMT1 P26358 1/20 0.41
DNMT3L Q9UJW3 1/20 0.41
DNMT3A Q9Y6K1 1/20 0.41
CES1 P23141 2/20 0.40
USP8 P40818 2/20 0.40
USP7 Q93009 2/20 0.40
TGM2 P21980 1/20 0.40
USP47 Q96K76 1/20 0.40
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
CYP3A4 P08684 3/20 0.39
TSHR P16473 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7819127 1.00 TDP2 (0.64) TDP2NSD2HK1PAX8S100A4
SCHEMBL7818893 1.00 TDP2 (0.64) TDP2NSD2HK1PAX8S100A4
SCHEMBL9643067 0.85 S100A4 (0.73) TDP2NSD2HK1PAX8S100A4
SCHEMBL7812020 0.81 TDP2 (0.60) TDP2NSD2HK1PAX8S100A4
SCHEMBL30003578 0.81 ESR2 (0.61) TDP2NSD2HK1PAX8S100A4
SCHEMBL23271822 0.81 ESR2 (0.61) TDP2NSD2HK1PAX8S100A4
SCHEMBL7812173 0.81 TDP2 (0.60) TDP2NSD2HK1PAX8S100A4
SCHEMBL30003080 0.81 TDP2 (0.60) TDP2NSD2HK1PAX8S100A4
SCHEMBL4229683 0.80 S100A4 (0.80) S100A4HSP90AA1PPOXIDO1DNMT1
SCHEMBL353693 0.80 S100A4 (0.80) S100A4HSP90AA1PPOXIDO1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed