Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477797 | 1.00 | FFAR1 (0.44) | FFAR1FFAR4HPGDMAOBPKM | |
| SCHEMBL1477283 | 0.86 | PKM (0.54) | HPGDMAOBPKMMAPTCA12 | |
| SCHEMBL12749278 | 0.81 | MAOB (0.41) | HPGDMAOBMAPTCYP3A4CYP2A6 | |
| SCHEMBL14037318 | 0.79 | MAOB (0.40) | HPGDMAOBMAPTCYP3A4CYP2A6 | |
| SCHEMBL21728096 | 0.79 | FFAR1 (0.44) | FFAR1FFAR4HPGDMAOBMAPT | |
| SCHEMBL28586710 | 0.79 | HPGD (0.41) | HPGDMAOBMAPTCA12CA2 | |
| SCHEMBL1477058 | 0.79 | LMNA (0.44) | HPGDMAOBMAPTTSHRLMNA | |
| SCHEMBL31177911 | 0.78 | HPGD (0.45) | HPGDMAOBMAPTCA12CA2 | |
| SCHEMBL24947180 | 0.78 | HPGD (0.38) | HPGDMAOBMAPTCA12CA2 | |
| SCHEMBL1477316 | 0.78 | MAOB (0.41) | HPGDMAOBMAPTCYP3A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653613-B1 | 1,3-DI-SUBSTITUTED KETENE COMPOUND AND APPLICATION THEREOF | BEBETTER MED INC (CN) | 2022-11-16 | — | — | EP | disclosed |