Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641485 | 0.79 | ESR1 (0.50) | CA2 | |
| SCHEMBL3939597 | 0.77 | POLB (0.41) | HRH3SMN1; SMN2ADRB2 | |
| SCHEMBL6482123 | 0.77 | ABAT (0.43) | HRH3 | |
| SCHEMBL17316474 | 0.76 | CA2 (0.52) | CA2SMN1; SMN2LMNATDP1 | |
| SCHEMBL11290860 | 0.76 | CA2 (0.80) | CA2 | |
| SCHEMBL15524912 | 0.73 | HRH3 (0.41) | HRH3SMN1; SMN2 | |
| SCHEMBL20267018 | 0.73 | OPRL1 (0.54) | HRH3SMN1; SMN2 | |
| SCHEMBL20300595 | 0.73 | DRD2 (0.41) | CA2HRH3 | |
| SCHEMBL28305762 | 0.72 | CA2 (0.47) | CA2 | |
| SCHEMBL7049643 | 0.72 | DRD2 (0.47) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323350-A1 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022219407-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS AG (CH) | 2022-10-20 | — | — | WO | disclosed |