SCHEMBL3000441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3012969	0.93	ALDH1A1 (0.47)	CYP4F2CYP4A11SMN1; SMN2RAB9AALDH1A1
	SCHEMBL31239046	0.93	ALDH1A1 (0.47)	CYP4F2CYP4A11SMN1; SMN2RAB9AALDH1A1
	SCHEMBL3005511	0.89	CYP4F2 (0.43)	CYP4F2CYP4A11SMN1; SMN2RAB9AALDH1A1
	SCHEMBL3006290	0.84	CYP4F2 (0.57)	CYP4F2CYP4A11SMN1; SMN2HPGDRAB9A
	SCHEMBL15800476	0.84	CYP4F2 (0.54)	CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP2C19
	SCHEMBL3010698	0.81	MRGPRX4 (0.45)	SMN1; SMN2RAB9AL3MBTL1SLC7A5TP53
	SCHEMBL29580473	0.81	MRGPRX4 (0.45)	SMN1; SMN2RAB9AL3MBTL1SLC7A5TP53
	SCHEMBL15344564	0.80	CYP4F2 (0.61)	CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP2C19
	SCHEMBL1067976	0.78	TDP1 (0.55)	SMN1; SMN2CYP1A2CYP2C19L3MBTL1ALDH1A1
	SCHEMBL3401255	0.77	CYP2D6 (0.48)	CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.