Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.60 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | ADH5 | P11766 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856871 | 1.00 | PFKFB3 (0.60) | PFKFB3GP6MAPTIDO1ALDH1A1 | |
| SCHEMBL940146 | 0.85 | GP6 (0.65) | PFKFB3GP6MAPTIDO1ALDH1A1 | |
| SCHEMBL4367955 | 0.84 | MAPT (0.69) | GP6MAPTIDO1ALDH1A1PIK3CD | |
| SCHEMBL4261812 | 0.80 | MAPT (0.60) | GP6MAPTIDO1ALDH1A1PIK3CD | |
| SCHEMBL17963197 | 0.80 | XDH (0.67) | NPC1RAB9APARP1XDHADH5 | |
| SCHEMBL12822128 | 0.79 | FGFR1 (0.45) | PFKFB3GP6MAPTPIK3CDPIK3CA | |
| SCHEMBL16947309 | 0.79 | — | — | |
| SCHEMBL4581907 | 0.78 | GP6 (0.51) | PFKFB3GP6MAPTIDO1ALDH1A1 | |
| SCHEMBL18234332 | 0.78 | — | — | |
| SCHEMBL21856968 | 0.77 | PFKFB3 (1.00) | PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |