Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006621 | 0.96 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| SCHEMBL30006542 | 0.93 | MERTK (0.40) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| SCHEMBL30005776 | 0.93 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| SCHEMBL30005790 | 0.91 | NAMPT (0.42) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Hydrochloric Acid SCHEMBL30006473 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| SCHEMBL30005065 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| SCHEMBL30005526 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1NPSR1POLB | |
| Hydrochloric Acid SCHEMBL30005731 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Hydrochloric Acid SCHEMBL30005778 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Hydrochloric Acid SCHEMBL30005582 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1NPSR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |