Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006021 | 0.94 | NAMPT (0.38) | NAMPTF13A1TGM2TGM1KIF18A | |
| SCHEMBL30004870 | 0.91 | ALDH1A1 (0.43) | NAMPTF13A1TGM2KMT2AALDH1A1 | |
| SCHEMBL30005005 | 0.91 | NAMPT (0.36) | NAMPTF13A1TGM2TGM1KIF18A | |
| SCHEMBL30006040 | 0.88 | ALDH1A1 (0.37) | NAMPTKIF18AKMT2ARXFP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30006508 | 0.88 | NAMPT (0.35) | NAMPTF13A1TGM2TGM1KIF18A | |
| SCHEMBL30006621 | 0.87 | ALDH1A1 (0.41) | NAMPTKMT2AALDH1A1MEN1NPSR1 | |
| Hydrochloric Acid SCHEMBL30006638 | 0.87 | NAMPT (0.35) | NAMPTKIF18AKMT2ARXFP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30005741 | 0.86 | ALDH1A1 (0.34) | NAMPTKIF18AKMT2ARXFP1ALDH1A1 | |
| SCHEMBL30005517 | 0.85 | ALDH1A1 (0.35) | KIF18AKMT2ARXFP1ALDH1A1MEN1 | |
| SCHEMBL30006778 | 0.84 | ALDH1A1 (0.48) | KIF18AKMT2ARXFP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |