Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | SPR | P35270 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20303285 | 1.00 | MAPT (1.00) | MAPTHPGDRAB9ASMN1; SMN2KDM4C | |
| SCHEMBL20320589 | 0.79 | MAPT (0.64) | MAPTHPGDRAB9ASMN1; SMN2SPR | |
| Hydrochloric Acid SCHEMBL20302609 | 0.78 | MAPT (0.62) | MAPTHPGDRAB9ASMN1; SMN2SPR | |
| SCHEMBL2155265 | 0.78 | MAPT (0.64) | MAPTHPGDRAB9ASMN1; SMN2KDM4C | |
| SCHEMBL960306 | 0.77 | MAPT (0.62) | MAPTRAB9ASMN1; SMN2SPRGAA | |
| SCHEMBL8267253 | 0.77 | RAB9A (0.71) | MAPTHPGDRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31069463 | 0.76 | SMN1; SMN2 (0.62) | MAPTRAB9ASMN1; SMN2KDM4ESPR | |
| SCHEMBL7280833 | 0.75 | HPGD (1.00) | MAPTHPGDRAB9ASMN1; SMN2KDM4C | |
| SCHEMBL13789318 | 0.75 | SMN1; SMN2 (0.74) | MAPTHPGDRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL13789403 | 0.75 | SMN1; SMN2 (0.74) | MAPTRAB9ASMN1; SMN2KDM4ESPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11472776-B2 | Quinazolinones that inhibit the formation of tau oligomers and their method of use | OLIGOMERIX, INC. (US) | 2022-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11472776-B2 | Quinazolinones that inhibit the formation of tau oligomers and their method of use | MAPT, PSEN1, APP | MAPT 1/4885HPGD 1765/4885RAB9A 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.