SCHEMBL2155265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28533431	0.84	KRAS (0.65)	MAPTKDM4EALDH1A1GAARXFP1
	SCHEMBL20303285	0.78	MAPT (1.00)	MAPTKDM4EALDH1A1GAARXFP1
	SCHEMBL30004904	0.78	MAPT (1.00)	MAPTKDM4EALDH1A1GAARXFP1
	SCHEMBL5123831	0.77	ALDH1A1 (0.72)	MAPTKDM4EALDH1A1GAARXFP1
	SCHEMBL13789324	0.75	TNKS2 (0.56)	KDM4EALDH1A1GAAHPGDKRAS
	SCHEMBL7280833	0.75	HPGD (1.00)	MAPTKDM4EALDH1A1GAARXFP1
	SCHEMBL30527145	0.75	KDM4C (1.00)	MAPTKDM4EALDH1A1GAARXFP1
	SCHEMBL20320595	0.75	KDM4C (1.00)	MAPTKDM4EALDH1A1GAARXFP1
	SCHEMBL30897311	0.74	HPGD (0.68)	MAPTKDM4EALDH1A1GAARXFP1
	Hydrochloric Acid SCHEMBL28547770	0.74	HPGD (0.97)	MAPTKDM4EALDH1A1GAARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.