Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23648065 | 1.00 | ACHE (0.32) | ACHEGRIN1GRIN2ABCHECA1 | |
| SCHEMBL23012452 | 0.85 | KDM1A (0.32) | ACHEGRIN1GRIN2ABCHEMAPT | |
| SCHEMBL6770814 | 0.80 | MEN1 (0.39) | ACHEGRIN1GRIN2ABCHECA1 | |
| SCHEMBL30572444 | 0.80 | MEN1 (0.39) | ACHEGRIN1GRIN2ABCHECA1 | |
| SCHEMBL13091632 | 0.78 | CYP3A4 (0.34) | ACHEGRIN1GRIN2ABCHEMAPT | |
| SCHEMBL13091629 | 0.77 | ACHE (0.32) | ACHEGRIN1GRIN2ABCHECA1 | |
| SCHEMBL22989890 | 0.77 | SOS1 (0.31) | — | |
| SCHEMBL26528126 | 0.77 | KDM4E (0.35) | MAPT | |
| SCHEMBL30888535 | 0.76 | SOS1 (0.30) | — | |
| SCHEMBL19995820 | 0.74 | NOS3 (0.36) | ACHEGRIN1GRIN2ABCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |