Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005172 | 0.82 | ENPP2 (0.45) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30005615 | 0.78 | GCK (0.55) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL2149410 | 0.77 | TSHR (0.52) | ALDH1A1LMNAHTR2AMEN1KMT2A | |
| SCHEMBL14538027 | 0.76 | NAMPT (0.46) | ALDH1A1MAPTHTR2AHTR2CKCNH2 | |
| SCHEMBL2148808 | 0.73 | TSHR (0.48) | ALDH1A1LMNAMEN1KMT2AHTR6 | |
| SCHEMBL31219768 | 0.73 | TSHR (0.48) | ALDH1A1LMNAMEN1KMT2AHTR6 | |
| SCHEMBL6120462 | 0.73 | HTR2A (0.40) | ALDH1A1LMNAHTR2AHTR2CKCNH2 | |
| SCHEMBL5428002 | 0.73 | CA12 (0.44) | ALDH1A1LMNASPRHTR2AHTR2C | |
| SCHEMBL20379865 | 0.72 | TSHR (0.46) | ALDH1A1LMNAMEN1KMT2AHTR6 | |
| SCHEMBL14501620 | 0.71 | HTR2A (0.52) | ALDH1A1HTR2AHTR2CKCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |