Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005392 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1ADRB1SMN1; SMN2MEN1 | |
| SCHEMBL3007916 | 0.79 | SMN1; SMN2 (0.58) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2148897 | 0.79 | CA2 (0.53) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17373706 | 0.79 | SIRT6 (0.51) | POLBALDH1A1SIRT6SMN1; SMN2ACHE | |
| SCHEMBL3012503 | 0.77 | MAPT (0.43) | ENPP2MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL2345848 | 0.76 | ACHE (0.51) | MAPTPOLBMEN1KMT2AACHE | |
| SCHEMBL1871990 | 0.75 | CA12 (0.47) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3005704 | 0.75 | SMN1; SMN2 (0.52) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20379733 | 0.75 | ACHE (0.50) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3020027 | 0.74 | MAPT (0.69) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |