Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005968 | 0.85 | ALDH1A1 (0.73) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005724 | 0.85 | ALDH1A1 (0.55) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005807 | 0.75 | ALDH1A1 (0.55) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005444 | 0.75 | ALDH1A1 (0.73) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005784 | 0.74 | ALDH1A1 (0.54) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30006634 | 0.74 | ALDH1A1 (0.71) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005654 | 0.74 | ALDH1A1 (0.55) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005902 | 0.74 | ALDH1A1 (0.55) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31518537 | 0.69 | ALDH1A1 (0.79) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005500 | 0.69 | KMT2A (0.59) | ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |