Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005737 | 0.88 | KMT2A (0.47) | KMT2AL3MBTL1POLBTSHRALDH1A1 | |
| SCHEMBL16569907 | 0.80 | KMT2A (0.66) | KMT2AL3MBTL1POLBTSHRKDM4E | |
| SCHEMBL6283810 | 0.79 | KMT2A (0.64) | KMT2AL3MBTL1POLBTSHRKDM4E | |
| SCHEMBL20683121 | 0.79 | KMT2A (0.64) | KMT2AL3MBTL1POLBTSHRKDM4E | |
| SCHEMBL7683509 | 0.79 | KMT2A (0.64) | KMT2AL3MBTL1POLBTSHRKDM4E | |
| SCHEMBL30005025 | 0.77 | KMT2A (0.61) | KMT2AL3MBTL1POLBTSHRKDM4E | |
| SCHEMBL30005525 | 0.76 | KMT2A (0.59) | KMT2AL3MBTL1POLBTSHRKDM4E | |
| SCHEMBL647372 | 0.75 | KMT2A (1.00) | KMT2AL3MBTL1POLBTSHRHSD17B10 | |
| SCHEMBL9629881 | 0.72 | TTBK1 (0.40) | KMT2APOLBTSHRKDM4EHSD17B10 | |
| SCHEMBL7555104 | 0.71 | KMT2A (0.66) | KMT2AL3MBTL1POLBTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |