Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23777734 | 0.85 | NOTUM (0.57) | NOTUMFAAHNPC1 | |
| SCHEMBL22054781 | 0.82 | SUV39H2 (0.45) | NOTUMSLC6A7CHRM4CHRM2CHRM1 | |
| SCHEMBL20139249 | 0.82 | CHRM4 (0.54) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL20139213 | 0.81 | FAAH (0.54) | NOTUMFAAHCHRM4SMONPC1 | |
| SCHEMBL27606539 | 0.81 | FAAH (0.54) | NOTUMFAAHCHRM4SMONPC1 | |
| SCHEMBL30005266 | 0.80 | SUV39H2 (0.51) | NOTUMSUV39H2 | |
| SCHEMBL4573042 | 0.80 | SLC6A7 (0.45) | SLC6A7FAAHCHRM4CHRM1NPC1 | |
| SCHEMBL31111518 | 0.79 | CHRM2 (0.57) | NOTUMFAAHCHRM4CHRM2CHRM1 | |
| SCHEMBL28604592 | 0.79 | TRPV1 (0.40) | SLC6A7CHRM2CHRM1SMO | |
| SCHEMBL28604594 | 0.79 | TRPV1 (0.40) | SLC6A7CHRM2CHRM1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |