Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 8/20 | 0.40 |
| ▸ | GCKR | Q14397 | 7/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17998 | 0.98 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10TDP1GCK | |
| SCHEMBL2643602 | 0.78 | KDM4E (0.67) | KDM4ETDP1GCKGCKRNOS3 | |
| SCHEMBL30565567 | 0.77 | KDM4E (0.64) | KDM4EGCKGCKRNOS3NOS2 | |
| SCHEMBL1700622 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10TDP1GCK | |
| SCHEMBL597932 | 0.77 | KDM4E (0.64) | KDM4EGCKGCKRNOS3NOS2 | |
| Hydrochloric Acid SCHEMBL27585913 | 0.75 | KDM4E (0.96) | KDM4EALDH1A1HSD17B10TDP1GCK | |
| SCHEMBL17509 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL29483829 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL651902 | 0.74 | ALDH1A1 (0.71) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL23625111 | 0.73 | KDM4E (0.60) | KDM4EGCKGCKRNOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |