SCHEMBL17509

SCHEMBL17509

O=S(=O)(Cl)c1ccc(Cl)nc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.56
MAPT P10636 1/20 0.55
POLB P06746 1/20 0.53
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 8/20 0.49
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
GAA P10253 2/20 0.47
PKM P14618 2/20 0.47
CYP2D6 P10635 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CYP2C19 P33261 1/20 0.45
EGFR P00533 1/20 0.44
NAPRT Q6XQN6 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483829 1.00 SMN1; SMN2 (0.56) SMN1; SMN2MAPTPOLBMEN1KMT2A
Hydrochloric Acid SCHEMBL4803286 0.98 SMN1; SMN2 (0.55) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL20210 0.83 SMN1; SMN2 (0.53) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL23904091 0.83 SMN1; SMN2 (0.53) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL3670962 0.80 MAPT (0.47) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL19055 0.80 SMN1; SMN2 (0.55) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL2633979 0.80 KDM4E (0.59) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL4804914 0.80 SMN1; SMN2 (0.59) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL4804922 0.80 KDM4E (0.59) SMN1; SMN2MAPTPOLBMEN1KMT2A
SCHEMBL188710 0.80 ALDH1A1 (0.63) SMN1; SMN2MAPTPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 991 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304543-B Preparation method and product of aryl sulfonamide containing norbornenyl and application of aryl sulfonamide 南京林业大学 2024-08-20 CN claimed
CN-115304543-A Preparation method of aryl sulfonamide containing norbornenyl, product and application thereof 南京林业大学 2022-11-08 CN claimed
CN-102603630-A O-aminobenzoic acid sulfonylation derivative as well as preparation method and application thereof UNIV BEIJING SCIENCE & TECH 2012-07-25 CN claimed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
US-20260116910-A1 POLYCYCLIC COMPOUNDS AND METHODS THEREOF HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN) 2026-04-30 US disclosed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 US disclosed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US disclosed
US-20260085067-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF BOUNDLESS BIO INC (US) 2026-03-26 US disclosed
EP-4695242-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 EP disclosed
EP-4210694-B1 PLASMA KALLIKREIN INHIBITORS MERCK SHARP & DOHME LLC (US) 2025-10-15 EP disclosed
US-20250270194-A1 PYRAZOLE-SUBSTITUTED CYCLOPENTANOL ESTER DERIVATIVE AND USE THEREOF CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2025-08-28 US disclosed
EP-0070481-B1 PHOTOGRAPHIC ELEMENTS EMPLOYING NONDIFFUSIBLE PYRIDYLAZO(DIALKYLAMINO)PHENOL MAGENTA DYE-RELEASING COMPOUNDS OR PRECURSORS THEREOF EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-10 EP disclosed
EP-0119050-A2 Dihydropyridine anti-ischaemic and antihypertensive agents Pfizer Limited (GB) 1984-09-19 EP disclosed
EP-0070481-A1 Photographic elements employing nondiffusible pyridylazo(dialkylamino)phenol magenta dye-releasing compounds or precursors thereof EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-26 EP disclosed
US-4368249-A Photographic products and processes employing novel nondiffusible pyridylazo(dialkylamino)phenol magenta dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1983-01-11 US disclosed
US-4367174-A Photographic products and processes employing novel nondiffusible pyridylazo(dialkylamino)phenol magenta dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1983-01-04 US disclosed
US-4357410-A Photographic products and processes employing novel nondiffusible pyridylazo(dialkylamino) phenol magenta dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1982-11-02 US disclosed
US-4273706-A Nondiffusible heterocyclylazonaphthol dye-releasing compounds EASTMAN KODAK COMPANY (US) 1981-06-16 US disclosed
US-4207104-A DIFFUSION TRANSFER TO FORM METALLIZED DYE IMAGE OF EXCELLENT STABILITY EASTMAN KODAK COMPANY (US) 1980-06-10 US disclosed
US-4204870-A METALLIZED DYES EASTMAN KODAK COMPANY (US) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof CYP4A11, CYP4B1, CYP4A22 SMN1; SMN2 4729/4885MAPT 2797/4885POLB 1807/4885
US-20260085067-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF RRM1, RRM2B, RRM2 SMN1; SMN2 1060/4885MAPT 3508/4885POLB 342/4885
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 SMN1; SMN2 3395/4885MAPT 4813/4885POLB 2549/4885
US-20250270194-A1 PYRAZOLE-SUBSTITUTED CYCLOPENTANOL ESTER DERIVATIVE AND USE THEREOF CYP51A1, CYP11B2, CYP11B1 SMN1; SMN2 4385/4885MAPT 2778/4885POLB 4103/4885
US-20260116910-A1 POLYCYCLIC COMPOUNDS AND METHODS THEREOF NR1H3, NR1H2, CPT1A SMN1; SMN2 1522/4885MAPT 3948/4885POLB 2006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.