Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880264 | 1.00 | LMNA (0.67) | LMNAKMT2AMEN1NPC1TDP1 | |
| SCHEMBL8920256 | 0.86 | LMNA (0.54) | LMNATP53GAAMAPTSLC6A3 | |
| SCHEMBL10280718 | 0.85 | LMNA (0.63) | LMNAKMT2AMEN1NPC1TDP1 | |
| SCHEMBL13522407 | 0.85 | LMNA (0.66) | LMNAKMT2AMEN1NPC1TDP1 | |
| SCHEMBL880483 | 0.84 | LMNA (0.62) | LMNAKMT2AMEN1NPC1TDP1 | |
| SCHEMBL880444 | 0.84 | TP53 (0.59) | LMNAKMT2AMEN1TP53MAPT | |
| SCHEMBL880376 | 0.83 | ALDH1A1 (0.58) | LMNAKMT2AMEN1NPC1TDP1 | |
| SCHEMBL7156373 | 0.83 | ALDH1A1 (0.58) | LMNAKMT2AMEN1NPC1TDP1 | |
| SCHEMBL12698414 | 0.83 | ALDH1A1 (0.58) | LMNAKMT2AMEN1NPC1TDP1 | |
| SCHEMBL10280290 | 0.82 | LMNA (0.70) | LMNAKMT2AMEN1NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072490-B | High-efficiency synthesis method of tipifarnib quinolinone intermediate | 中国海洋大学 | 2022-08-16 | — | — | CN | claimed |
| CN-113072490-B | High-efficiency synthesis method of tipifarnib quinolinone intermediate | 中国海洋大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-113072490-B | High-efficiency synthesis method of tipifarnib quinolinone intermediate | 中国海洋大学 | 2022-08-16 | — | — | CN | disclosed |