Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR1F | P30939 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 3/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624211 | 1.00 | LPL (0.33) | LPLLIPGJAK2BTKSCD | |
| SCHEMBL21624315 | 0.80 | JAK2 (0.33) | LPLLIPGJAK2BTKSCD | |
| SCHEMBL29968226 | 0.80 | JAK2 (0.33) | LPLLIPGJAK2BTKSCD | |
| SCHEMBL21636302 | 0.80 | LPL (0.37) | LPLLIPGJAK2BTK | |
| SCHEMBL21636512 | 0.79 | LPL (0.31) | LPLLIPGJAK2BTK | |
| SCHEMBL21624158 | 0.78 | PIK3C3 (0.38) | LPLLIPGJAK2BTK | |
| SCHEMBL21636300 | 0.76 | JAK2 (0.31) | JAK2BTK | |
| SCHEMBL21624120 | 0.74 | HTR2C (0.35) | LPLLIPGJAK2BTK | |
| SCHEMBL21624362 | 0.74 | LPL (0.33) | LPLLIPGJAK2BTK | |
| SCHEMBL21624108 | 0.74 | HTR6 (0.36) | LPLLIPGJAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |