Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15804316 | 0.95 | MEN1 (0.49) | STSMEN1KMT2ADRD2POLB | |
| SCHEMBL3119720 | 0.92 | STS (0.45) | STSMEN1KMT2ADRD2POLB | |
| SCHEMBL3385458 | 0.91 | MEN1 (0.43) | STSMEN1KMT2ADRD2POLB | |
| SCHEMBL29892887 | 0.87 | STS (0.50) | STSMEN1KMT2ADRD2POLB | |
| SCHEMBL3028439 | 0.87 | STS (0.50) | STSMEN1KMT2ADRD2POLB | |
| SCHEMBL15804317 | 0.87 | MEN1 (0.45) | STSMEN1KMT2ADRD2POLB | |
| SCHEMBL21143968 | 0.86 | DRD2 (0.46) | MEN1KMT2ADRD2POLBOPRD1 | |
| SCHEMBL557597 | 0.86 | DRD2 (0.61) | STSMEN1KMT2ADRD2SMN1; SMN2 | |
| SCHEMBL20744372 | 0.86 | JAK2 (0.46) | STSMEN1KMT2ADRD2POLB | |
| SCHEMBL2425082 | 0.84 | RORC (0.41) | STSMEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |