Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SOD1 | P00441 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751920 | 0.84 | NQO1 (0.46) | NQO1TSHRTDP1 | |
| SCHEMBL1547677 | 0.81 | MAPT (0.54) | MAPTSOD1CYP2C19NQO1TSHR | |
| SCHEMBL24854715 | 0.80 | KMT2A (0.51) | — | |
| SCHEMBL27730066 | 0.80 | NQO1 (0.50) | MAPTSOD1CYP2C19NQO1TSHR | |
| SCHEMBL3780893 | 0.77 | NQO1 (0.50) | MAPTSOD1CYP2C19NQO1TSHR | |
| SCHEMBL8751807 | 0.76 | NQO1 (0.63) | MAPTNQO1TSHRTDP1 | |
| SCHEMBL16101859 | 0.76 | NQO1 (0.39) | NQO1TSHRL3MBTL1TDP1 | |
| SCHEMBL16033984 | 0.75 | NQO1 (0.34) | MAPTNQO1 | |
| SCHEMBL23907053 | 0.74 | NQO1 (0.37) | NQO1TSHRTDP1 | |
| SCHEMBL28001063 | 0.74 | KDM4E (0.51) | NQO1L3MBTL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |