SCHEMBL8751920

SCHEMBL8751920

CCOCOc1cc(OCOCC)cc(OCOCC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.46
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ESR1 P03372 2/20 0.35
AHR P35869 1/20 0.35
LTA4H P09960 2/20 0.34
PTPN1 P18031 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALDH1A1 P00352 2/20 0.32
PLA2G2A P14555 1/20 0.31
PARP10 Q53GL7 1/20 0.31
RELA Q04206 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16101859 0.91 NQO1 (0.39) NQO1TSHRTDP1ESR1AHR
SCHEMBL8751807 0.86 NQO1 (0.63) NQO1TSHRTDP1LTA4HPTPN1
SCHEMBL6156485 0.85 CYP4F2 (0.36) NQO1LTA4HALDH1A1
SCHEMBL23907053 0.84 NQO1 (0.37) NQO1TSHRTDP1
SCHEMBL30005939 0.84 MAPT (0.47) NQO1TSHRTDP1
SCHEMBL6156345 0.83 ALDH1A1 (0.39) NQO1TDP1ESR1AHRPTPN1
SCHEMBL6154744 0.83 ESR1 (0.39) NQO1ESR1AHRPTPN1RELA
SCHEMBL1665107 0.82 TP53 (0.47) NQO1TSHRTDP1LTA4HTP53
SCHEMBL6154971 0.82 PLA2G2A (0.57) TSHRTDP1TP53PLA2G2ARELA
SCHEMBL23907028 0.80 TTR (0.39) NQO1ESR1LTA4HCYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579420-B1 Negative working resist material and pattern forming process WAKO PURE CHEM IND LTD (JP) 1997-03-05 EP disclosed
US-5389491-A Negative working resist composition MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1995-02-14 US disclosed