Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509019 | 0.89 | HSD11B1 (0.65) | HTTHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL12813309 | 0.84 | HTT (0.67) | HTTALDH1A1MAPTKMT2AGAA | |
| SCHEMBL5257034 | 0.84 | HTT (0.67) | HTTHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL30005036 | 0.84 | HTT (0.67) | HTTALDH1A1MAPTKMT2AGAA | |
| SCHEMBL3214214 | 0.84 | ALDH1A1 (0.71) | HTTALDH1A1MAPTKMT2AGAA | |
| SCHEMBL11508240 | 0.83 | MEN1 (0.65) | HTTHSD11B1ALDH1A1KMT2AGAA | |
| SCHEMBL1711126 | 0.81 | HSD11B1 (0.70) | HSD11B1ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL9310984 | 0.81 | ALDH1A1 (0.67) | HTTALDH1A1MAPTKMT2AGAA | |
| SCHEMBL14094672 | 0.81 | ALDH1A1 (0.62) | HTTALDH1A1MAPTKMT2AGAA | |
| SCHEMBL14127823 | 0.80 | ALDH1A1 (0.61) | HTTHSD11B1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |