Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624286 | 1.00 | MAPT (0.51) | MAPTSMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL14254883 | 0.81 | HTT (0.55) | MAPTSMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL21624307 | 0.80 | MAPT (0.51) | MAPTSMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL1282557 | 0.79 | PDK1 (0.45) | MAPTMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL14254877 | 0.78 | HTT (0.60) | MAPTSMN1; SMN2PKMHTTLMNA | |
| SCHEMBL2212472 | 0.76 | KDM4E (0.42) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL3774635 | 0.76 | CETP (0.59) | MAPTSMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL2946590 | 0.75 | MEN1 (0.46) | MAPTSMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL13264093 | 0.74 | L3MBTL1 (0.43) | MAPTPKMHTTL3MBTL1LMNA | |
| SCHEMBL14254888 | 0.74 | CYP1A2 (0.43) | MAPTSMN1; SMN2HTTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771046-B | Other substituted triazoloquinoxaline derivatives | 格吕伦塔尔有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |