Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26310436 | 1.00 | TPH1 (0.39) | TPH1TPH2 | |
| SCHEMBL27171424 | 1.00 | TPH1 (0.39) | TPH1TPH2 | |
| SCHEMBL26308060 | 0.92 | TPH1 (0.36) | TPH1TPH2 | |
| SCHEMBL24253761 | 0.86 | TPH1 (0.41) | TPH1TPH2 | |
| SCHEMBL24253553 | 0.86 | TPH1 (0.41) | TPH1TPH2 | |
| SCHEMBL24253760 | 0.86 | TPH1 (0.41) | TPH1TPH2 | |
| SCHEMBL30006852 | 0.84 | TPH1 (0.38) | TPH1TPH2 | |
| SCHEMBL24253958 | 0.78 | PDE10A (0.31) | — | |
| SCHEMBL30424075 | 0.78 | PDE10A (0.31) | — | |
| SCHEMBL30423951 | 0.77 | TPH1 (0.38) | TPH1TPH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | claimed |
| EP-4323062-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | Novartis AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022219546-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | NOVARTIS AG (CH) | 2022-10-20 | — | — | WO | disclosed |