SCHEMBL30006146

SCHEMBL30006146

O=C(O)[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](NS(=O)(=O)O)C(O)O[C@@H]2COS(=O)(=O)O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.57
BDNF P23560 3/20 0.46
PTN P21246 2/20 0.46
MDK P21741 2/20 0.46
SERPINC1 P01008 2/20 0.46
F2 P00734 1/20 0.46
HPSE Q9Y251 10/20 0.39
PF4 P02776 2/20 0.39
FGF1 P05230 1/20 0.35
FGF2 P09038 1/20 0.35
IFNG P01579 1/20 0.35
BMP2 P12643 1/20 0.35
CCL2 P13500 1/20 0.35
VEGFA P15692 1/20 0.35
SELP P16109 1/20 0.35
BMP6 P22004 1/20 0.35
CXCL12 P48061 1/20 0.35
CCL11 P51671 1/20 0.35
WNT3A P56704 1/20 0.35
SELPLG Q14242 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13311345 0.91 F10 (0.64) F10BDNFPTNMDKSERPINC1
SCHEMBL4593793 0.91 F10 (0.64) F10BDNFPTNMDKSERPINC1
SCHEMBL14670002 0.91 F10 (0.64) F10BDNFPTNMDKSERPINC1
SCHEMBL15416845 0.86 F10 (0.57) F10BDNFPTNMDKSERPINC1
SCHEMBL23337007 0.81 F10 (0.64) F10BDNFPTNMDKSERPINC1
SCHEMBL29308178 0.80 F10 (0.79) F10BDNFPTNMDKSERPINC1
SCHEMBL12514534 0.80 F10 (0.60) F10BDNFPTNMDKSERPINC1
SCHEMBL16509456 0.80 F10 (0.77) F10BDNFPTNMDKSERPINC1
SCHEMBL23135895 0.79 F10 (0.62) F10BDNFPTNMDKSERPINC1
SCHEMBL29647566 0.78 F10 (0.60) F10BDNFPTNMDKSERPINC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3232193-B1 DIAGNOSIS OF MPS I DISORDERS BY MEASURING NON-REDUCING ENDS OF GAGS AFTER ENZYMATIC DIGEST BIOMARIN PHARM INC (US) 2023-03-01 EP claimed
US-20220404379-A1 SEQUENCING METHOD, SYSTEM AND KIT OF LOW MOLECULAR WEIGHT HEPARIN OLIGOSACCHARIDES SHANDONG UNIVERSITY (CN) 2022-12-22 US claimed
US-20220404375-A1 ANTIBODIES TO DISULFATED HEPARIN DISACCHARIDE IN THE DIAGNOSIS OF NEUROPATHY WASHINGTON UNIVERSITY 2022-12-22 US claimed
CN-113393904-B Method and system for detecting low-molecular heparin sugar chain sequence and sequencing kit 山东大学 2022-10-18 CN claimed
US-20250281523-A1 SULFATED GLYCOSAMINOGLYCAN COMPOUNDS, METHODS, AND USES THEREOF CALIFORNIA INST OF TECHN (US) 2025-09-11 US disclosed
CN-118308338-A PL35 family chondroitin sulfate lyase and encoding gene and application thereof 山东第二医科大学 2024-07-09 CN disclosed
US-11903963-B2 Short-acting heparin-based anticoagulant compounds and methods THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-02-20 US disclosed
EP-3232193-B1 DIAGNOSIS OF MPS I DISORDERS BY MEASURING NON-REDUCING ENDS OF GAGS AFTER ENZYMATIC DIGEST BIOMARIN PHARM INC (US) 2023-03-01 EP disclosed
US-20220404379-A1 SEQUENCING METHOD, SYSTEM AND KIT OF LOW MOLECULAR WEIGHT HEPARIN OLIGOSACCHARIDES SHANDONG UNIVERSITY (CN) 2022-12-22 US disclosed
US-20220404375-A1 ANTIBODIES TO DISULFATED HEPARIN DISACCHARIDE IN THE DIAGNOSIS OF NEUROPATHY WASHINGTON UNIVERSITY 2022-12-22 US disclosed
CN-113393904-B Method and system for detecting low-molecular heparin sugar chain sequence and sequencing kit 山东大学 2022-10-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281523-A1 SULFATED GLYCOSAMINOGLYCAN COMPOUNDS, METHODS, AND USES THEREOF HPSE, CSGALNACT1, DDOST F10 2036/4885BDNF 375/4885PTN 398/4885
US-11903963-B2 Short-acting heparin-based anticoagulant compounds and methods HPSE, STS, SULT1A1 F10 425/4885BDNF 4395/4885PTN 1592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.