Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.64 |
| ▸ | SERPINC1 | P01008 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | BDNF | P23560 | 3/20 | 0.46 |
| ▸ | PTN | P21246 | 2/20 | 0.46 |
| ▸ | MDK | P21741 | 2/20 | 0.46 |
| ▸ | FGF1 | P05230 | 2/20 | 0.42 |
| ▸ | FGF2 | P09038 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.42 |
| ▸ | CCL2 | P13500 | 2/20 | 0.42 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | CCL5 | P13501 | 1/20 | 0.42 |
| ▸ | BMP2 | P12643 | 2/20 | 0.38 |
| ▸ | VEGFA | P15692 | 2/20 | 0.38 |
| ▸ | SHH | Q15465 | 2/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.38 |
| ▸ | PF4 | P02776 | 2/20 | 0.37 |
| ▸ | IFNG | P01579 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311345 | 1.00 | F10 (0.64) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL14670002 | 1.00 | F10 (0.64) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL15416845 | 0.91 | F10 (0.57) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL30006146 | 0.91 | F10 (0.57) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL23337007 | 0.90 | F10 (0.64) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL29308178 | 0.89 | F10 (0.79) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL23135895 | 0.89 | F10 (0.62) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL16509456 | 0.86 | F10 (0.77) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL15417563 | 0.85 | F10 (0.53) | F10SERPINC1F2BDNFPTN | |
| SCHEMBL27448112 | 0.84 | BDNF (0.60) | F10SERPINC1F2BDNFPTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942929-A2 | HEPARAN SULFATE GLYCOSAMINOGLYCAN LYASE AND USES THEREOF | Momenta Pharmaceuticals, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056218-A2 | HEPARAN SULFATE GLYCOSAMINOGLYCAN LYASE AND USES THEREOF | MOMENTA PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |