Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MOGAT2 | Q3SYC2 | 5/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 4/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23648062 | 1.00 | PDK2 (0.42) | PDK2MOGAT2HSD11B1ARAKR1B1 | |
| SCHEMBL21624380 | 0.93 | PDK2 (0.42) | PDK2MOGAT2ARAKR1B1 | |
| SCHEMBL23648074 | 0.82 | PDK2 (0.32) | PDK2 | |
| SCHEMBL23647755 | 0.79 | MOGAT2 (0.38) | MOGAT2ARAKR1B1 | |
| SCHEMBL30668488 | 0.76 | MOGAT2 (0.38) | MOGAT2ARAKR1B1 | |
| SCHEMBL21624341 | 0.76 | MOGAT2 (0.38) | MOGAT2ARAKR1B1 | |
| SCHEMBL21624382 | 0.75 | PDK2 (0.32) | PDK2 | |
| SCHEMBL23648075 | 0.75 | ALDH1A1 (0.39) | MOGAT2AR | |
| SCHEMBL23648081 | 0.75 | AR (0.46) | MOGAT2AR | |
| SCHEMBL21624337 | 0.72 | PDK1 (0.44) | PDK2MOGAT2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |