SCHEMBL30006319

SCHEMBL30006319

CCCCCCC(Br)Cc1cccc(C)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.45
LTB4R Q15722 6/20 0.36
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MTOR P42345 1/20 0.34
PMP22 Q01453 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PLIN1 O60240 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
PLIN5 Q00G26 1/20 0.34
ABHD5 Q8WTS1 1/20 0.34
CSNK1E P49674 1/20 0.33
CCR1 P32246 1/20 0.32
CCR8 P51685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30006067 0.94 KCNH2 (0.40) KCNH2LTB4RALDH1A1SMN1; SMN2MTOR
SCHEMBL30006203 0.85 ALDH1A1 (0.37) LTB4RALDH1A1SMN1; SMN2MTORPMP22
SCHEMBL16228294 0.75 KCNH2 (0.78) KCNH2SMN1; SMN2CCR1CCR8
SCHEMBL22299298 0.75 KCNH2 (0.78) KCNH2SMN1; SMN2CCR1CCR8
SCHEMBL9971347 0.75 KCNH2 (0.78) KCNH2SMN1; SMN2CCR1CCR8
SCHEMBL16228298 0.75 KCNH2 (0.78) KCNH2SMN1; SMN2CCR1CCR8
SCHEMBL26162438 0.75 KCNH2 (0.78) KCNH2SMN1; SMN2CCR1CCR8
SCHEMBL16227752 0.75 KCNH2 (0.78) KCNH2SMN1; SMN2CCR1CCR8
Heptane SCHEMBL27729190 0.74 KCNH2 (0.56) KCNH2SMN1; SMN2MAPTCCR1CCR8
SCHEMBL10373980 0.73 KCNH2 (0.74) KCNH2SMN1; SMN2CCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907257-B Method for catalyzing non-activated olefin halogenated pyridine through visible light induction 中国科学院大连化学物理研究所 2023-11-24 CN disclosed
CN-114907257-A Method for catalyzing non-activated olefin halopyridination through visible light induction 中国科学院大连化学物理研究所 2022-08-16 CN disclosed